Hsueh‐Cheng Chiang

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

Zhenyu Cai, Siriporn Jitkaew, Jie Zhao et al. · Nature Cell Biology · 2013 · 1.3K citations · Full text

Protein Function, Signal Transduction, Apoptosis +10

BACE1, a Major Determinant of Selective Vulnerability of the Brain to Amyloid-β Amyloidogenesis, is Essential for Cognitive, Emotional, and Synaptic Functions

Fiona M. Laird, Huaibin Cai, Alena Savonenko et al. · Journal of Neuroscience · 2005 · 518 citations · Full text

Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis

Wonchul Shin, Lihao Ge, Gianvito Arpino et al. · Cell · 2018 · 215 citations · Full text

Membrane Fusion, Live Cells, Cell Organelle +9

Epidermal growth factor receptor is a preferred target for treating Amyloid-β–induced memory loss

Lei Wang, Hsueh‐Cheng Chiang, Wenjuan Wu et al. · Proceedings of the National Academy of Sciences · 2012 · 185 citations · Full text

Aβ42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila

Koichi Iijima, Hsueh‐Cheng Chiang, Stephen Hearn et al. · PLoS ONE · 2008 · 167 citations · Full text

Genetics, Aβ42 Mutants, Molecular Genetics +16