Suzanne R. Morgan

Discovery of an Orally Efficacious Inhibitor of Coagulation Factor Xa Which Incorporates a Neutral P₁Ligand

Yong Mi Choi-Sledeski, Robert E. Kearney, Gregory Poli et al. · Journal of Medicinal Chemistry · 2003 · 78 citations · Full text

Orally Efficacious Inhibitor, Pharmaceutical Science, Pharmacotherapy +18

Optimization of the β-Aminoester class of factor Xa inhibitors. part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity

Kevin R. Guertin, Charles J. Gardner, Scott I. Klein et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 52 citations · Full text

Thrombosis, Medicinal Chemistry, Biochemistry +10

Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

William R. Ewing, Michael R. Becker, Vincent E. Manetta et al. · Journal of Medicinal Chemistry · 1999 · 42 citations · Full text

Selective Inhibitors, Pharmacotherapy, Chemical Biology +19

Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa

Scott I. Klein, Mark Czekaj, Charles J. Gardner et al. · Journal of Medicinal Chemistry · 1998 · 39 citations · Full text

Vitro Potency, Pharmacotherapy, Initial Structure−activity Relationships +20

Sulfonamidopyrrolidinone Factor Xa Inhibitors:  Potency and Selectivity Enhancements via P-1 and P-4 Optimization

Yong Mi Choi-Sledeski, Daniel McGarry, Daniel M. Green et al. · Journal of Medicinal Chemistry · 1999 · 36 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Pharmacotherapy +18