Lawrence Chun - Concepedia

Concepedia

Author

Lawrence Chun

Deciphera Pharmaceuticals (United States)

Also Known As

L E Chun, L. Chun, L. E. Chun, L.E Chun, Lawrence Chun, Lawrence E. Chun, Lawrence E. Chun

28

Publications

2.2K

Citations

17

H-Index

40

Concepts

All Affiliations

Deciphera Pharmaceuticals (United States)University of Washington Virginia Mason Bainbridge Island Medical Center Nivalis Therapeutics (United States)Eli Lilly (United States)

LC

About

Lawrence Chun is an author at Deciphera Pharmaceuticals (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	1.2K
2	Biochemistry	4	4	193
3	Natural Sciences	2	2	109
4	Engineering	1	1	27
5	Allergy	1	1	57

Lawrence Chun

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17

Publications

2.2K

Citations

17

H-Index

	Year	Citations
Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers Sheng-Bin Peng, James R. Henry, Michael D. Kaufman, Cancer Cell Ly3009120 LeadsRaf IsoformsMedicineAnti-cancer AgentTumor Suppressor	2015	305
Effects of proteoglycan extraction on the tensile behavior of articular cartilage Mary Beth Schmidt, Van C. Mow, Lawrence Chun, Journal of Orthopaedic Research®	1990	290
Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants Bryan D. Smith, Michael D. Kaufman, Wei-Ping Lu, Cancer Cell Pdgfra VariantsOncogenic AgentMedicineDrug-resistant KitReceptor Tyrosine Kinase	2019	270
Sites of stromelysin cleavage in collagen types II, IX, X, and XI of cartilage. Jiann-Jiu Wu, Michael W. Lark, Lawrence Chun, Journal of Biological Chemistry	1991	262
Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036 Wayne W. Chan, Scott Wise, Michael D. Kaufman, Cancer Cell Switch-control Inhibitor Dcc-2036Signal TransductionSignaling PathwayConformational Control InhibitionCell Regulation	2011	204
The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors Allison S. Harney, George S. Karagiannis, Jeanine Pignatelli, Molecular Cancer Therapeutics	2017	162
Ultrasonic propagation properties of articular cartilage at 100 MHz Diane H. Agemura, William D. O’Brien, John E. Olerud, The Journal of the Acoustical Society of America	1990	98
Preliminary observations of chondral abrasion in a canine model. Roy D. Altman, Jonathan Kates, Lawrence Chun, Annals of the Rheumatic Diseases	1992	96
Mechanism of Inhibition for N6022, a First-in-Class Drug Targeting <i>S</i>-Nitrosoglutathione Reductase Louis S. Green, Lawrence Chun, Aaron K. Patton, Biochemistry Inflammatory Lung DiseaseLung InflammationNitric OxideFormaldehyde AdductChemical Biology	2012	85
Discovery of 1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-<i>d</i>]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against <i>BRAF</i> or <i>RAS</i> Mutant Tumor Cells James R. Henry, Michael D. Kaufman, Sheng-Bin Peng, Journal of Medicinal Chemistry Kinase InhibitorsPharmaceutical ChemistryTumor BiologyMolecular PharmacologyMedicinal Chemistry	2015	84

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