Bryan D. Smith

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers

Sheng-Bin Peng, James R. Henry, Michael D. Kaufman et al. · Cancer Cell · 2015 · 305 citations · Full text

Ly3009120 Leads, Raf Isoforms, Medicine +8

Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants

Bryan D. Smith, Michael D. Kaufman, Wei-Ping Lu et al. · Cancer Cell · 2019 · 270 citations

Pdgfra Variants, Oncogenic Agent, Medicine +9

Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036

Wayne W. Chan, Scott Wise, Michael D. Kaufman et al. · Cancer Cell · 2011 · 204 citations · Full text

Switch-control Inhibitor Dcc-2036, Signal Transduction, Signaling Pathway +9

The Selective Tie2 Inhibitor Rebastinib Blocks Recruitment and Function of Tie2Hi Macrophages in Breast Cancer and Pancreatic Neuroendocrine Tumors

Allison S. Harney, George S. Karagiannis, Jeanine Pignatelli et al. · Molecular Cancer Therapeutics · 2017 · 162 citations · Full text

Biomimetic Synthesis of the Putative Cytotoxin Peroxynitrite, ONOO-, and Its Characterization as a Tetramethylammonium Salt

D. Scott Bohle, Bernhard Hansert, Scott Paulson et al. · Journal of the American Chemical Society · 1994 · 122 citations

Bioorganic Chemistry, Toxinology, Chemical Analysis +21