Paul R. Reid

Discovery of Tertiary Sulfonamides as Potent Liver X Receptor Antagonists

William J. Zuercher, Richard G. Buckholz, Nino Campobasso et al. · Journal of Medicinal Chemistry · 2010 · 95 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Allosteric Antagonism of Insect Odorant Receptor Ion Channels

Patrick L. Jones, Gregory M. Pask, Ian M. Romaine et al. · PLoS ONE · 2012 · 77 citations · Full text

Life Sciences, Entomology, Neuroscience +16

Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): The development of ML169, an MLPCN probe

Paul R. Reid, Thomas M. Bridges, Douglas J. Sheffler et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Activation of heme biosynthesis by a small molecule that is toxic to fermenting <i>Staphylococcus aureus</i>

Laura A. Mike, Brendan F. Dutter, Devin L. Stauff et al. · Proceedings of the National Academy of Sciences · 2013 · 51 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Targeting Selective Activation of M₁ for the Treatment of Alzheimer’s Disease: Further Chemical Optimization and Pharmacological Characterization of the M₁ Positive Allosteric Modulator ML169

James C. Tarr, Mark Turlington, Paul R. Reid et al. · ACS Chemical Neuroscience · 2012 · 41 citations

Medicine, Medicinal Chemistry, Pharmacology +17