James C. Tarr

Selective Activation of M₄Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Michael Bubser, Thomas M. Bridges, Ditte Dencker et al. · ACS Chemical Neuroscience · 2014 · 155 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

Nicholas F. Pelz, Zhiguo Bian, Bin Zhao et al. · Journal of Medicinal Chemistry · 2016 · 147 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100

Nellie Byun, Michael Grannan, Michael Bubser et al. · Neuropsychopharmacology · 2014 · 122 citations · Full text

Medicine, Neuroscience, Pharmacology +12

Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer

Taekyu Lee, Plamen P. Christov, Subrata Shaw et al. · Journal of Medicinal Chemistry · 2019 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13

Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design

Subrata Shaw, Zhiguo Bian, Bin Zhao et al. · Journal of Medicinal Chemistry · 2018 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15