James C. Tarr

Selective Activation of M₄Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Michael Bubser, Thomas M. Bridges, Ditte Dencker et al. · ACS Chemical Neuroscience · 2014 · 150 citations · Full text

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

Nicholas F. Pelz, Zhiguo Bian, Bin Zhao et al. · Journal of Medicinal Chemistry · 2016 · 143 citations · Full text

Drug Target, Molecular Biology, Tumor Biology +16

Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100

Nellie Byun, Michael Grannan, Michael Bubser et al. · Neuropsychopharmacology · 2014 · 119 citations · Full text

Psychiatry, Functional Selectivity, Medicine +9

Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design

Subrata Shaw, Zhiguo Bian, Bin Zhao et al. · Journal of Medicinal Chemistry · 2018 · 64 citations · Full text

Pharmacotherapy, Pharmaceutical Chemistry, Tumor Biology +16

Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer

Taekyu Lee, Plamen P. Christov, Subrata Shaw et al. · Journal of Medicinal Chemistry · 2019 · 64 citations · Full text

Hematological Malignancy, Tumor Biology, Mouse Xenograft Models +15