Gijs den Besten

Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation

Gijs den Besten, Aycha Bleeker, Albert Gerding et al. · Diabetes · 2015 · 1.1K citations

Life Sciences, Nutrition, Nutritional Sciences +17

Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids

Gijs den Besten, Katja Lange, Rick Havinga et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2013 · 603 citations

Life Sciences, Physiology, Bioenergetics +13

Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1

Gijs den Besten, Albert Gerding, Theo H. van Dijk et al. · PLoS ONE · 2015 · 127 citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +16

Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload

Karen van Eunen, Sereh M. J. Simons, Albert Gerding et al. · PLoS Computational Biology · 2013 · 82 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +16

The Short-Chain Fatty Acid Uptake Fluxes by Mice on a Guar Gum Supplemented Diet Associate with Amelioration of Major Biomarkers of the Metabolic Syndrome

Gijs den Besten, Rick Havinga, Aycha Bleeker et al. · PLoS ONE · 2014 · 77 citations · Full text

Life Sciences, Nutrition, Nutritional Sciences +11