Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

Angelika Bierhaus, Thomas Fleming, Stoyan Stoyanov, +30

Nature Medicine

NeurophysiologyPain MedicineMedicineDiabetesDiabetic Neuropathy +11

Effects on weight loss and glycemic control with SAR441255, a potent unimolecular peptide GLP-1/GIP/GCG receptor triagonist

Martin Bossart, Michael Wagner, Ralf Elvert, +23

Cell Metabolism

Increased Energy Expenditure Contributes More to the Body Weight-Reducing Effect of Rimonabant than Reduced Food Intake in Candy-Fed Wistar Rats

Andreas W. Herling, Susanne Kilp, Ralf Elvert, +2

Endocrinology

NutritionReduced Food IntakeEnergy ExpenditureFood IntakeExperimental Nutrition +16

Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists

Andreas Evers, Torsten Haack, M. Lorenz, +10

Journal of Medicinal Chemistry

BiochemistryFunctional SelectivityMedicineDrug DiscoveryPeptide Library +12

A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders

Aimo Kannt, Sridharan Rajagopal, Sanjay Venkatachalapathi Kadnur, +26

Scientific Reports

On the Use of the Time Axis for Ecological Separation: Diel Rhythms as an Evolutionary Constraint

Noga Kronfeld‐Schor, Tamar Dayan, Ralf Elvert, +3

The American Naturalist

BiologyTime AxisTheoretical EcologyNatural SciencesEvolutionary Biology +5

Impact of IVC housing on emotionality and fear learning in male C3HeB/FeJ and C57BL/6J mice

Magdalena Kallnik, Ralf Elvert, Nicole Ehrhardt, +8

Mammalian Genome

Neurobiological MechanismBehavioral SciencesBehavioral NeuroscienceAffective NeuroscienceNeuroendocrinology +10

Genetic Nicotinamide <i>N</i>-Methyltransferase (<i>Nnmt</i>) Deficiency in Male Mice Improves Insulin Sensitivity in Diet-Induced Obesity but Does Not Affect Glucose Tolerance

Sebastian Brachs, James Polack, Maria Brachs, +8

Diabetes

Loss of the Actin Remodeler Eps8 Causes Intestinal Defects and Improved Metabolic Status in Mice

Arianna Tocchetti, Charlotte Blanche Ekalle Soppo, Fabio Zani, +20

PLoS ONE

Cardiorespiratory and metabolic reactions during entrance into torpor in dormice, <i>Glis glis</i>

Ralf Elvert, Gerhard Heldmaier

Journal of Experimental Biology