Deborah D. Giera

Pharmacological and Pharmacokinetic Properties of a Structurally Novel, Potent, and Selective Metabotropic Glutamate 2/3 Receptor Agonist: In Vitro Characterization of Agonist (–)-(1 R,4 S,5 S,6 S)-4-Amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic Acid (LY404039)

Linda M. Rorick‐Kehn, Bryan G. Johnson, Jennifer Burkey et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 93 citations

Medicine, Pharmacokinetics, Pharmacology +14

Enzymatic Sulfation of Steroids: I. The Enzymatic Basis for the Sex Difference in Cortisol Sulfation by Rat Liver Preparations

Sanford S. Singer, Deborah D. Giera, James R. Johnson et al. · Endocrinology · 1976 · 84 citations

Life Sciences, Biochemistry, Endocrinology +17

Acyl Sulfonamide Anti-Proliferatives:  Benzene Substituent Structure−Activity Relationships for a Novel Class of Antitumor Agents

Karen L. Lobb, Philip A. Hipskind, James Aikins et al. · Journal of Medicinal Chemistry · 2004 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Synthesis and Metabotropic Glutamate Receptor Activity of S-Oxidized Variants of (−)-4-Amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate:  Identification of Potent, Selective, and Orally Bioavailable Agonists for mGlu2/3 Receptors

James A. Monn, Steven M. Massey, Matthew J. Valli et al. · Journal of Medicinal Chemistry · 2006 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Dibasic Benzo[<i>b</i>]thiophene Derivatives as a Novel Class of Active Site-Directed Thrombin Inhibitors. 1. Determination of the Serine Protease Selectivity, Structure−Activity Relationships, and Binding Orientation

Daniel J. Sall, Jolie Bastian, John A. Buben et al. · Journal of Medicinal Chemistry · 1997 · 54 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10