Andrew A. Sproul

Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

Dominik Paquet, Dylan Kwart, Chen Antonia et al. · Nature · 2016 · 1K citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

Tyler M. Lu, Sean Houghton, Tarig Magdeldin et al. · Proceedings of the National Academy of Sciences · 2021 · 222 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +15

Characterization and Molecular Profiling of PSEN1 Familial Alzheimer's Disease iPSC-Derived Neural Progenitors

Andrew A. Sproul, Samson Jacob, Deborah Prè et al. · PLoS ONE · 2014 · 185 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2 N141I neurons

Maitane Ortiz‐Virumbrales, Cesar L. Moreno, Ilya Kruglikov et al. · Acta Neuropathologica Communications · 2017 · 170 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

A Time Course Analysis of the Electrophysiological Properties of Neurons Differentiated from Human Induced Pluripotent Stem Cells (iPSCs)

Deborah Prè, Michael W. Nestor, Andrew A. Sproul et al. · PLoS ONE · 2014 · 127 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17