A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

Liuliu Yang, Yuling Han, Benjamin E. Nilsson-Payant, +34

Cell stem cell

Induced Pluripotent Stem CellHuman CellsViral PathogenesisVirologyStem Cell Research +5

Identification of SARS-CoV-2 inhibitors using lung and colonic organoids

Yuling Han, Xiaohua Duan, Liuliu Yang, +31

Nature

MedicineColonic OrganoidsAntiviral Drug DevelopmentAntiviral DrugPharmacology +2

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

Tyler M. Lu, Sean Houghton, Tarig Magdeldin, +13

Proceedings of the National Academy of Sciences

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids

Yuling Han, Liuliu Yang, Xiaohua Duan, +26

Inflammatory responses in the placenta upon SARS-CoV-2 infection late in pregnancy

Lissenya B. Argueta, Lauretta A. Lacko, Yaron Bram, +23

iScience

ImmunologyViral PathogenesisGynecologyPathologyCovid-19 +18

An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts

Liuliu Yang, Yuling Han, Fabrice Jaffré, +21

Circulation Research

InflammationMacrophage-mediated InflammationVisual LanguageGraphic DesignImmunology +9

Reversal of emphysema by restoration of pulmonary endothelial cells

Shu Hisata, Alexandra C. Racanelli, Pouneh Kermani, +16

The Journal of Experimental Medicine

Acute Lung InjuryInflammatory Lung DiseaseEndothelial CellsLung InflammationImmunology +16

Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction

Jesús M. Gómez-Salinero, Franco Izzo, Yang Lin, +15

Cell stem cell

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer

Hyejin Choi, Jiehui Deng, Shuai Li, +12

Cell Reports

SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

Wei Yong Gu, Hua Wang, Xiaofeng Huang, +22

Cell stem cell

Ileum-colon ConversionDevelopmental BiologyColorectal CancerStem Cell ResearchGut Barrier +3