Denise Gautreau

New bicyclic cannabinoid receptor-1 (CB1-R) antagonists

Philip A. Carpino, David A. Griffith, Subas M. Sakya et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 42 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Design of a Potent CB₁Receptor Antagonist Series: Potential Scaffold for Peripherally-Targeted Agents

Robert L. Dow, Philip A. Carpino, Denise Gautreau et al. · ACS Medicinal Chemistry Letters · 2012 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Optimization of triazole-based TGR5 agonists towards orally available agents

Kentaro Futatsugi, Kevin B. Bahnck, Martin Brenner et al. · MedChemComm · 2012 · 31 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Chemical Probe Identification Platform for Orphan GPCRs Using Focused Compound Screening: GPR39 as a Case Example

Markus Boehm, David Hepworth, Paula M. Loria et al. · ACS Medicinal Chemistry Letters · 2013 · 28 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

In vitro and in vivo pharmacology of CP-945,598, a potent and selective cannabinoid CB1 receptor antagonist for the management of obesity

John R. Hadcock, David A. Griffith, Phillip Iredale et al. · Biochemical and Biophysical Research Communications · 2010 · 24 citations

Medicine, Medicinal Chemistry, Pharmacology +10