Hyun Seop Tae

Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics

Ashley R. Schneekloth, Mathieu Pucheault, Hyun Seop Tae et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 574 citations · Full text

Proteomic Technology, Protein Function, Biochemistry +12

Targeting the von Hippel–Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1α Interaction

Dennis L. Buckley, Inge Van Molle, Peter C. Gareiss et al. · Journal of the American Chemical Society · 2012 · 540 citations · Full text

Small-molecule hydrophobic tagging–induced degradation of HaloTag fusion proteins

Taavi K. Neklesa, Hyun Seop Tae, Ashley R. Schneekloth et al. · Nature Chemical Biology · 2011 · 403 citations · Full text

Protein Chemistry, Protein Folding, Natural Sciences +4

Small‐Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

Dennis L. Buckley, Jeffrey L. Gustafson, Inge Van Molle et al. · Angewandte Chemie International Edition · 2012 · 280 citations · Full text

Pharmacological targeting of the pseudokinase Her3

Ting Xie, Sang Min Lim, Kenneth D. Westover et al. · Nature Chemical Biology · 2014 · 197 citations · Full text

Novel Therapy, Medicine, Therapeutic Efficacy +4