Risk Factors for Cisplatin-Induced Nephrotoxicity and Potential of Magnesium Supplementation for Renal Protection

Yasuhiro Kidera, Hisato Kawakami, Tsutomu Sakiyama, +13

PLoS ONE

Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

Masashi Yanae, Masanobu Tsubaki, Takao Satou, +4

Journal of Experimental & Clinical Cancer Research

Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway

Yasuhiro Kidera, Masanobu Tsubaki, Yuzuru Yamazoe, +10

Journal of Experimental & Clinical Cancer Research

Tamoxifen inhibits tumor cell invasion and metastasis in mouse melanoma through suppression of PKC/MEK/ERK and PKC/PI3K/Akt pathways

Hiroshi Matsuoka, Masanobu Tsubaki, Yuzuru Yamazoe, +5

Experimental Cell Research

MedicineMouse MelanomaMelanomaPathologyPkc/pi3k/akt Pathways +6

Blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathways by statins reduces the expression of bFGF, HGF, and TGF-β as angiogenic factors in mouse osteosarcoma

Masanobu Tsubaki, Yuzuru Yamazoe, Masashi Yanae, +6

Cytokine

Ras/pi3k/akt PathwaysStatins ReducesMouse OsteosarcomaAngiogenesisImmunology +6

Overexpression of MDR1 and survivin, and decreased Bim expression mediate multidrug-resistance in multiple myeloma cells

Masanobu Tsubaki, Takao Satou, Tatsuki Itoh, +7

Leukemia Research

Hematological MalignancyTumor BiologyOncologyMedicineMultiple Myeloma Cells +5

Mangiferin induces apoptosis by suppressing Bcl-xL and XIAP expressions and nuclear entry of NF-κB in HL-60 cells

Kaori Shoji, Masanobu Tsubaki, Yuzuru Yamazoe, +9

Archives of Pharmacal Research

InflammationMangiferin Induces ApoptosisMitophagyXiap ExpressionsMedicine +9

Dimethylfumarate inhibits tumor cell invasion and metastasis by suppressing the expression and activities of matrix metalloproteinases in melanoma cells

Yuzuru Yamazoe, Masanobu Tsubaki, Hiroshi Matsuoka, +10

Cell Biology International

High-dose dexamethasone plus antihistamine prevents colorectal cancer patients treated with modified FOLFOX6 from hypersensitivity reactions induced by oxaliplatin

Yasuhiro Kidera, Taroh Satoh, Shinya Ueda, +18

International Journal of Clinical Oncology

Modified Folfox6OncologyAllergyMedicineHigh-dose Dexamethasone +6

Decreased brain FDG uptake in patients with extensive non-Hodgkin’s lymphoma lesions

Kohei Hanaoka, Makoto Hosono, Taro Shimono, +7

Annals of Nuclear Medicine

Neuro-oncologyLymphoid NeoplasiaBrain Fdg UptakeNeurologyBrain Lesion +4