Alexandra Wuest

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

Cassandra Burdziak, Direna Alonso‐Curbelo, Thomas Walle et al. · Science · 2023 · 207 citations · Full text

Medicine, Cell Biology, Oncology +17

Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants

Francisco J. Sánchez‐Rivera, Bianca J. Diaz, Edward R. Kastenhuber et al. · Nature Biotechnology · 2022 · 129 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +14

MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis

Francisco M. Barriga, Kaloyan M. Tsanov, Yu-Jui Ho et al. · Nature Cancer · 2022 · 120 citations · Full text

Medicine, Genetics, Oncology +17

High-throughput evaluation of genetic variants with prime editing sensor libraries

Samuel I. Gould, Alexandra Wuest, Kexin Dong et al. · Nature Biotechnology · 2024 · 64 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Generation of precision preclinical cancer models using regulated in vivo base editing

Alyna Katti, Adrián Vega‐Pérez, Miguel Foronda et al. · Nature Biotechnology · 2023 · 31 citations · Full text

Medicine, Molecular Biology, Oncology +12