Alexandra Wuest

Epigenetic plasticity cooperates with cell-cell interactions to direct pancreatic tumorigenesis

Cassandra Burdziak, Direna Alonso‐Curbelo, Thomas Walle et al. · Science · 2023 · 173 citations · Full text

Epigenetic Change, Epigenetics, Tumor Biology +18

Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants

Francisco J. Sánchez‐Rivera, Bianca J. Diaz, Edward R. Kastenhuber et al. · Nature Biotechnology · 2022 · 119 citations · Full text

High-throughput Engineering, Functional Genomics, Engineering +13

MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis

Francisco M. Barriga, Kaloyan M. Tsanov, Yu-Jui Ho et al. · Nature Cancer · 2022 · 104 citations · Full text

High-throughput evaluation of genetic variants with prime editing sensor libraries

Samuel I. Gould, Alexandra Wuest, Kexin Dong et al. · Nature Biotechnology · 2024 · 56 citations · Full text

Genetics, Molecular Biology, Tumor Genomes +22

Generation of precision preclinical cancer models using regulated in vivo base editing

Alyna Katti, Adrián Vega‐Pérez, Miguel Foronda et al. · Nature Biotechnology · 2023 · 28 citations · Full text

Tumor Heterogeneity, Preclinical Models, Vivo Base Editing +12