Robert Strome

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice

Martin Citron, David Westaway, Weiming Xia et al. · Nature Medicine · 1997 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +17

The cellular prion protein binds copper in vivo

David R. Brown, Kefeng Qin, Jochen Herms et al. · Nature · 1997 · 1.3K citations

Life Sciences, Biochemistry, Molecular Biology +7

Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

M. Azhar Chishti, Dun-Shen Yang, Christopher Janus et al. · Journal of Biological Chemistry · 2001 · 954 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

Richard C. Moore, Inyoul Y. Lee, Gregory L. Silverman et al. · Journal of Molecular Biology · 1999 · 519 citations

Veterinary Medicine, Neurology, Neuroscience +16

Protein generation with evolutionary diffusion: sequence is all you need

Sarah Alamdari, Nitya Thakkar, Rianne van den Berg et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 152 citations · Full text

Life Sciences, Bioinformatics, Evolutionary Biology +16