Brennan K. Smith

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Stephen L. Pinkosky, Roger S. Newton, Emily A. Day et al. · Nature Communications · 2016 · 481 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

Simon A. Hawley, Rebecca J. Ford, Brennan K. Smith et al. · Diabetes · 2016 · 386 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Lack of Adipocyte AMPK Exacerbates Insulin Resistance and Hepatic Steatosis through Brown and Beige Adipose Tissue Function

Emilio P. Mottillo, Eric M. Desjardins, Justin D. Crane et al. · Cell Metabolism · 2016 · 323 citations · Full text

Medicine, Biochemistry, Physiology +16

Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss

Emily A. Day, Rebecca J. Ford, Brennan K. Smith et al. · Nature Metabolism · 2019 · 296 citations

Life Sciences, Endocrinology, Pharmacology +13

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

Linda A. Villani, Brennan K. Smith, Katarina Marcinko et al. · Molecular Metabolism · 2016 · 244 citations · Full text

Medicine, Oncology, Pharmacology +17