Lian-Yong Chen

Study of chiral auxiliaries for the intramolecular [2+2] cycloaddition of a keteniminium salt to an olefinic double bond. A new asymmetric synthesis of cyclobutanones.

Lian-Yong Chen, Léon Ghosez · Tetrahedron Letters · 1990 · 87 citations

Natural Sciences, Chemistry, Organic Chemistry +11

Asymmetric Synthesis of Substituted 2-Azaspiro[3.5]nonan-1-ones:  An Enantioselective Synthesis of the Cholesterol Absorption Inhibitor (+)-SCH 54016

Lian-Yong Chen, A. S. Zaks, Samuel Chackalamannil et al. · The Journal of Organic Chemistry · 1996 · 61 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Trans diastereoselective synthesis of 3-alkyl substituted β-lactams via the acid chloride-imine reaction of nonactivated acid chlorides

Margaret Browne, Duane A. Burnett, Mary Ann Caplen et al. · Tetrahedron Letters · 1995 · 51 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Intramolecular cycloadditions of keteniminium salts. A practical asymmetric synthesis of prostaglandins.

Lian-Yong Chen, Léon Ghosez · Tetrahedron Asymmetry · 1991 · 38 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

A short multigram asymmetric synthesis of prostanoid scaffolds

Dominique Depré, Lian-Yong Chen, Léon Ghosez · Tetrahedron · 2003 · 24 citations

Engineering, Bioengineering, Drug Design +12