Samuel Chackalamannil

Author

Also Known As

Chackalamannil, S., S Chackalamannil, S. CHACKALAMANNIL, S. Chackalamannil, SAMUEL CHACKALAMANNIL, Samuel Chackalamannil

116

Publications

2.4K

Citations

H-Index

Concepts

All Affiliations

AIL Research (United States)Merck & Co., Inc., Rahway, NJ, USA (United States)Duke University

About

Samuel Chackalamannil is an author at AIL Research (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	22	36	1.4K
2	Biochemistry	18	27	1.2K
3	Natural Sciences	17	20	1K
4	Engineering	8	8	247
5	Arts	1	1	55

Samuel Chackalamannil

Publications

2.2K

Citations

H-Index

Page 1

	Year	Citations
Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity Samuel Chackalamannil, Yuguang Wang, William J. Greenlee, Journal of Medicinal Chemistry ImmunologyCardiovascular PharmacologyPharmacotherapyNatural Product HimbacineThrombosis	2008	267
Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents Samuel Chackalamannil, Yan Xia, William J. Greenlee, Journal of Medicinal Chemistry ImmunologyPharmacotherapyNovel Thrombin ReceptorNovel Antithrombotic AgentsNatural Product Himbacine	2005	123
Design and synthesis of piperidinyl piperidine analogues as potent and selective M2 muscarinic receptor antagonists Yuguang Wang, Samuel Chackalamannil, Zhiyong Hu, Bioorganic & Medicinal Chemistry Letters Piperidinyl Piperidine AnaloguesFunctional SelectivityMedicineMechanism Of ActionPharmacological Agent	2000	96
A Highly Efficient Total Synthesis of (+)-Himbacine Samuel Chackalamannil, Robert J. Davies, Theodros Asberom, Journal of the American Chemical Society Chemical EngineeringBiosynthesisBioorganic ChemistryEngineeringBiochemistry	1996	85
Potent Tetracyclic Guanine Inhibitors of PDE1 and PDE5 Cyclic Guanosine Monophosphate Phosphodiesterases with Oral Antihypertensive Activity Ho-Sam Ahn, Ana Bercovici, George Boykow, Journal of Medicinal Chemistry	1997	80
Simultaneous determination of a drug candidate and its metabolite in rat plasma samples using ultrafast monolithic column high‐performance liquid chromatography/tandem mass spectrometry Yunsheng Hsieh, Gangfeng Wang, Yuguang Wang, Rapid Communications in Mass Spectrometry	2002	78
Asymmetric Synthesis of Substituted 2-Azaspiro[3.5]nonan-1-ones: An Enantioselective Synthesis of the Cholesterol Absorption Inhibitor (+)-SCH 54016 Lian-Yong Chen, A. S. Zaks, Samuel Chackalamannil, The Journal of Organic Chemistry Asymmetric CatalysisMedicinal ChemistryBiochemistryNatural SciencesMedicine	1996	61
Identification of Novel Cannabinoid CB1 Receptor Antagonists by Using Virtual Screening with a Pharmacophore Model Hongwu Wang, Ruth A. Duffy, George Boykow, Journal of Medicinal Chemistry Drug TargetHit IdentificationAzetidinone Cb1 AntagonistsPharmacotherapyCannabinoid Pharmacology	2008	59
Synthetic studies toward aflavinine: a synthesis of 3-demethylaflavinine via a [2 + 2 + 2] annulation Samuel J. Danishefsky, Samuel Chackalamannil, Peter W. Harrison, Journal of the American Chemical Society Molecular SciencesBioorganic ChemistryBiochemistryDonut IconSynthetic Studies	1985	59
Total Synthesis of (+)-Himbacine and (+)-Himbeline Samuel Chackalamannil, Robert J. Davies, Yuguang Wang, The Journal of Organic Chemistry	1999	58

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