George Boykow

Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity

Samuel Chackalamannil, Yuguang Wang, William J. Greenlee et al. · Journal of Medicinal Chemistry · 2008 · 267 citations · Full text

Immunology, Cardiovascular Pharmacology, Pharmacotherapy +21

Inhibition of cellular action of thrombin by N3-cyclopropyl-7-{[4-(1-methylethyl)phenyl]methyl}-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine (SCH 79797), a nonpeptide thrombin receptor antagonist

Ho-Sam Ahn, Carolyn Foster, George Boykow et al. · Biochemical Pharmacology · 2000 · 139 citations

Thrombopoiesis, Thrombosis, Medicinal Chemistry +10

Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate.

Ira Tabas, William J. Rosoff, George Boykow · Journal of Biological Chemistry · 1988 · 136 citations · Full text

Cholesterol Oxidase-accessible Cholesterol, Molecular Biology, Oxidative Stress +16

Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents

Samuel Chackalamannil, Yan Xia, William J. Greenlee et al. · Journal of Medicinal Chemistry · 2005 · 123 citations · Full text

Immunology, Pharmacotherapy, Novel Thrombin Receptor +18

Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity.

Ira Tabas, George Boykow, Alan R. Tall · Journal of Clinical Investigation · 1987 · 85 citations · Full text

Lipid Peroxidation, Immunology, Arterial Wall Macrophages +19