Louis De Muynck

Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs

Jie Jiang, Qiang Zhu, Tania F. Gendron et al. · Neuron · 2016 · 530 citations · Full text

Natural Sciences, Als/ftd-linked Repeat Expansions, Molecular Biology +5

Progranulin is Neurotrophic In Vivo and Protects against a Mutant TDP-43 Induced Axonopathy

Angela S. Laird, Annelies Van Hoecke, Louis De Muynck et al. · PLoS ONE · 2010 · 144 citations · Full text

Neuroregeneration, Molecular Neuroscience, Developmental Biology +14

Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo

Sander Beel, Matthieu Moisse, Louis De Muynck et al. · Human Molecular Genetics · 2017 · 139 citations · Full text

Restoration of Progranulin Expression Rescues Cortical Neuron Generation in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia

Susanna Raitano, Laura Ordovás, Louis De Muynck et al. · Stem Cell Reports · 2014 · 85 citations · Full text

Microglial Upregulation of Progranulin as a Marker of Motor Neuron Degeneration

Thomas Philips, Louis De Muynck, Hoai Nguyen Thi Thu et al. · Journal of Neuropathology & Experimental Neurology · 2010 · 75 citations · Full text