Don O. Somers

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA ₂ Inhibitor

Nicholas D. Measom, Kenneth Down, David J. Hirst et al. · ACS Medicinal Chemistry Letters · 2016 · 234 citations · Full text

Exploring Ligand Stability in Protein Crystal Structures Using Binding Pose Metadynamics

Lucia Fusani, David Scott Palmer, Don O. Somers et al. · Journal of Chemical Information and Modeling · 2020 · 134 citations · Full text

Protein Assembly, Molecular Biology, Computational Chemistry +18

Heterogeneity of neurons in the subnucleus interpolaris of the cat

Don O. Somers, W. Michael Panneton · Brain Research · 1984 · 84 citations

Subnucleus Interpolaris, Neural Mechanism, Neurodynamics +11

Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library

Hongfeng Deng, Jingye Zhou, Flora S. Sundersingh et al. · ACS Medicinal Chemistry Letters · 2015 · 82 citations · Full text

Combinatorial Chemistry, Drug Target, Bioorganic Chemistry +24

Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity

Richard Angell, Paul Bamborough, Jacky B. Buckton et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 72 citations · Full text

Medicinal Chemistry, Vivo Activity, Chemoprevention Strategy +11