MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

Jürgen Bernhagen, Regina M. Krohn, Hongqi Lue, +15

Nature Medicine

InflammationCxc Chemokine ReceptorsCytokineChemokine BiologySignal Transduction +12

Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity

Hongqi Lue, Michael Thiele, Joakim Franz, +7

Oncogene

InflammationCytokineSignal TransductionAkt PathwaySignaling Pathway +9

A functional heteromeric MIF receptor formed by CD74 and CXCR4

Verena Schwartz, Hongqi Lue, Sandra Kraemer, +6

FEBS Letters

ImmunologyImmune RegulationImmunologic MechanismCd4 T Cell ResponsesCd74/cxcr4 Complexes +16

Regulated secretion of macrophage migration inhibitory factor is mediated by a non‐classical pathway involving an ABC transporter

Oliver Flieger, André Engling, Richard Bucala, +3

FEBS Letters

The <i>D</i> -dopachrome tautomerase ( <i>DDT</i> ) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF)

Melanie Merk, Swen Zierow, Lin Leng, +13

Proceedings of the National Academy of Sciences

Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity

Hongqi Lue, Aphrodite Kapurniotu, Günter Fingerle‐Rowson, +6

Cellular Signalling

Signal TransductionTransient ActivationSignaling PathwayReceptor Tyrosine KinaseSrc Kinase Activity +7

Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment

Christian Weber, Sandra Kraemer, Maik Drechsler, +5

Proceedings of the National Academy of Sciences

Immune RegulationImmunologyMif FunctionsImmunologic MechanismImmune System +19

Activation of the JNK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on CXCR4 and CD74

Hongqi Lue, Manfred Dewor, Lin Leng, +2

Cellular Signalling

InflammationCytokineSignal TransductionSignaling PathwayImmune Cell Development +7

Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer

Eva Verjans, Erik Noetzel, Nuran Bektas, +6

BMC Cancer

A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth Regulation

Günter Fingerle-Rowson, Dayananda Rao Kaleswarapu, Corinna Schlander, +15

Molecular and Cellular Biology

ImmunologyCell ProliferationCell GrowthCancer BiologyCellular Physiology +16