Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity

Hongqi Lue, Michael Thiele, Joakim Franz, +7

Oncogene

InflammationCytokineSignal TransductionAkt PathwaySignaling Pathway +9

Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity

Hongqi Lue, Aphrodite Kapurniotu, Günter Fingerle‐Rowson, +6

Cellular Signalling

Signal TransductionTransient ActivationSignaling PathwayReceptor Tyrosine KinaseSrc Kinase Activity +7

Stabilization of Atherosclerotic Plaques by Blockade of Macrophage Migration Inhibitory Factor After Vascular Injury in Apolipoprotein E–Deficient Mice

Andreas Schober, Jürgen Bernhagen, Michael Thiele, +5

Circulation

The Cytokine Macrophage Migration Inhibitory Factor Reduces Pro-Oxidative Stress-Induced Apoptosis

Mai Tuyet Nguyen, Hongqi Lue, Robert Kleemann, +6

The Journal of Immunology

ApoptosisImmunologyCell DeathCell Death MechanismsRedox Biology +15

Human Anti-Macrophage Migration Inhibitory Factor Antibodies Inhibit Growth of Human Prostate Cancer Cells <i>In Vitro</i> and <i>In Vivo</i>

Filza Hussain, Michael Freissmuth, Dirk Völkel, +8

Molecular Cancer Therapeutics

Neutralization of Macrophage Migration Inhibitory Factor (MIF) by Fully Human Antibodies Correlates with Their Specificity for the β-Sheet Structure of MIF

Randolf J. Kerschbaumer, Manfred Rieger, Dirk Völkel, +14

Journal of Biological Chemistry

Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions

Michael Thiele, Randolf J. Kerschbaumer, Frederick W.K. Tam, +21

The Journal of Immunology

Healthy SubjectsImmunologySelective TargetingInnate ImmunityImmune System +18

Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif

Anke Burger‐Kentischer, Doris Finkelmeier, Michael Thiele, +4

FEBS Letters

A chemically defined production process for highly attenuated poxviruses

Ingo Jordan, Stefan Northoff, Michael Thiele, +10

Biologicals

Viral ReplicationSynthetic VirologyPathogenesisVirologyDefined Production Process +2

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer

Alexander Schinagl, Michael Thiele, Patrice Douillard, +6

Oncotarget

Drug TargetHealthy SubjectsImmunologyCell DeathPathology +14