Hirokazu Ueno

Nicotine Enhances Human Vascular Endothelial Cell Expression of ICAM-1 and VCAM-1 Via Protein Kinase C, p38 Mitogen-Activated Protein Kinase, NF-κB, and AP-1

Hirokazu Ueno, Sanjeev Pradhan, D. Schlessel et al. · Cardiovascular Toxicology · 2006 · 78 citations

Inflammation, Molecular Physiology, Nicotine +7

Nicotine induces mitogen-activated protein kinase dependent vascular smooth muscle cell migration

Gabriele Di Luozzo, Sanjeev Pradhan, Ajay K. Dhadwal et al. · Atherosclerosis · 2004 · 53 citations

Signal Transduction, Molecular Physiology, Medicine +8

Application of Structure-Based Design and Parallel Chemistry to Identify a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor

Christopher J. Helal, Eric P. Arnold, Tracey Boyden et al. · Journal of Medicinal Chemistry · 2017 · 32 citations · Full text

Combinatorial Chemistry, Drug Target, Psychopharmacology +23

Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor

Kim F. McClure, Margaret Jackson, Kimberly O. Cameron et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 27 citations · Full text

Signal Transduction, Cns-targeted Inverse Agonists, Functional Selectivity +10

Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate

Christopher J. Helal, Eric P. Arnold, Tracey Boyden et al. · Journal of Medicinal Chemistry · 2018 · 27 citations · Full text