Shazia Keily

Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors

Jean‐Damien Charrier, Andrew T. Miller, David P. Kay et al. · Journal of Medicinal Chemistry · 2011 · 61 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases

Juan‐Miguel Jimenez, Dean Boyall, Guy Brenchley et al. · Journal of Medicinal Chemistry · 2013 · 49 citations · Full text

Life Sciences, Immunology, Medicinal Chemistry +15

Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis

Philip N. Collier, Heather Twin, Ronald M. A. Knegtel et al. · ACS Medicinal Chemistry Letters · 2019 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Solvent Sustainability in Drug Discovery: Where Are We Now, and How Can We Improve?

Paul Richardson, Marian C. Bryan, Louis J. Diorazio et al. · Journal of Medicinal Chemistry · 2025 · 12 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +14