Suman Shanker

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

J. Perry Hall, Amy Brault, Fabien Vincent et al. · PLoS ONE · 2017 · 157 citations · Full text

Crystal structures of interleukin 17A and its complex with IL-17 receptor A

Shenping Liu, Xi Song, Boris A. Chrunyk et al. · Nature Communications · 2013 · 140 citations · Full text

Inflammation, Cytokine, Molecular Immunology +11

Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications

Andreas Maderna, Matthew Doroski, Chakrapani Subramanyam et al. · Journal of Medicinal Chemistry · 2014 · 130 citations

Nanotherapeutics, Lead Auristatin, Peptide Science +20

The catalytic mechanism of cyclic GMP‐AMP synthase (cGAS) and implications for innate immunity and inhibition

J. Perry Hall, Erik C. Ralph, Suman Shanker et al. · Protein Science · 2017 · 64 citations · Full text

Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

Shenping Liu, Leslie Dakin, Xing Li et al. · Scientific Reports · 2016 · 60 citations · Full text