Yi Tan

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways

Xiang Wang, Xinxin Chen, Wenqian Zhou et al. · Acta Pharmaceutica Sinica B · 2021 · 481 citations · Full text

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

Yi Tan, Tomonaga Ichikawa, Jinqing Li et al. · Diabetes · 2011 · 388 citations · Full text

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

Yang Bai, Wenpeng Cui, Ying Xin et al. · Journal of Molecular and Cellular Cardiology · 2013 · 271 citations

Reductive Stress, Metabolic Syndrome, Cardiomyopathy +14

Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy

Junlian Gu, Yanli Cheng, Hao Wu et al. · Diabetes · 2016 · 191 citations · Full text

Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway

Zhiguo Zhang, Shudong Wang, Shanshan Zhou et al. · Journal of Molecular and Cellular Cardiology · 2014 · 189 citations

Metabolic Syndrome, Lkb1/ampk Pathway, Cardiomyopathy +12