Yi Tan

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways

Xiang Wang, Xinxin Chen, Wenqian Zhou et al. · Acta Pharmaceutica Sinica B · 2021 · 504 citations · Full text

Life Sciences, Cardiology, Cell Biology +15

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

Yi Tan, Tomonaga Ichikawa, Jinqing Li et al. · Diabetes · 2011 · 395 citations · Full text

Life Sciences, Biochemistry, Cardiology +17

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

Yang Bai, Wenpeng Cui, Ying Xin et al. · Journal of Molecular and Cellular Cardiology · 2013 · 273 citations

Life Sciences, Cell Biology, Molecular Biology +16

Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy

Junlian Gu, Yanli Cheng, Hao Wu et al. · Diabetes · 2016 · 196 citations

Medicine, Cardiology, Endocrinology +17

Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway

Zhiguo Zhang, Shudong Wang, Shanshan Zhou et al. · Journal of Molecular and Cellular Cardiology · 2014 · 189 citations

Life Sciences, Biochemistry, Pharmacology +11