Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo - Concepedia

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Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress–Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

DOI Full Paper Access

388

Citations

27

References

2011

Year

Yi Tan, Tomonaga Ichikawa, Jinqing Li, Qiusheng Si, Huaitao Yang, Xiangbai Chen, Curtis Goldblatt, Colin J. Meyer, Xiaokun Li, Lu Cai,

Abstract

ERK-mediated suppression of Nrf2 activity leads to the oxidative stress-induced insulin resistance in adult cardiomyocytes and downregulated glucose utilization in the diabetic heart.

References

	Year	Citations

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