Diabetic cardiomyopathy and its mechanisms: Role of oxidative stress and damage

Quan Liu, Shudong Wang, Lu Cai

Journal of Diabetes Investigation

Heart FailureLipid PeroxidationInflammation-induced Oxidative StressOxidative StressMetabolic Syndrome +15

Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy

Junlian Gu, Yanli Cheng, Hao Wu, +10

Diabetes

Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway

Zhiguo Zhang, Shudong Wang, Shanshan Zhou, +9

Journal of Molecular and Cellular Cardiology

Metabolic SyndromeLkb1/ampk PathwayCardiomyopathyBiochemistryMedicine +10

Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice

Jingjing Zhang, Yanli Cheng, Junlian Gu, +12

Clinical Science

Heart FailureDiabetic MiceImmunologyCardiovascular PharmacologyFgf21 Gene +23

Cardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway

Shudong Wang, Yonggang Wang, Zhiguo Zhang, +2

Cell Death and Disease

ImmunologyCardiovascular PharmacologyPathologyCell DeathRenal Inflammation +19

Inhibition of HDAC3 prevents diabetic cardiomyopathy in OVE26 mice via epigenetic regulation of DUSP5-ERK1/2 pathway

Zheng Xu, Qian Tong, Zhiguo Zhang, +7

Clinical Science

Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway

Chi Zhang, Zhifeng Huang, Junlian Gu, +10

Diabetologia

FibrosisAngiogenesisDevelopmental BiologyMedicineCell Death +8

Broccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/db T2DM mice

Zheng Xu, Shudong Wang, Honglei Ji, +7

Scientific Reports

Lipid PeroxidationDb/db T2dm MiceInsulin SignalingOxidative StressMetabolic Syndrome +14

Long Noncoding RNA lncCAMTA1 Promotes Proliferation and Cancer Stem Cell-Like Properties of Liver Cancer by Inhibiting CAMTA1

Lijuan Ding, Yan Li, Shudong Wang, +7

International Journal of Molecular Sciences

Hcc Cell ProliferationSystems BiologyGene ExpressionCancer Cell BiologyLong Non-coding Rna +13

Zinc rescues obesity‐induced cardiac hypertrophy <i>via</i> stimulating metallothionein to suppress oxidative stress‐activated <scp>BCL</scp>10/<scp>CARD</scp>9/p38 <scp>MAPK</scp> pathway

Shudong Wang, Junlian Gu, Zheng Xu, +11

Journal of Cellular and Molecular Medicine