Yosuke Nishigaya

The Asymmetric Total Synthesis of (+)‐Cytotrienin A, an Ansamycin‐Type Anticancer Drug

Yujiro Hayashi, Mitsuru Shoji, Hayato Ishikawa et al. · Angewandte Chemie International Edition · 2008 · 57 citations

Bioorganic Chemistry, 21-Membered Macrolactam, Pharmacotherapy +22

A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression

Shohei Takase, Takashi Hiroyama, Fumiyuki Shirai et al. · Nature Communications · 2023 · 38 citations · Full text

Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents

Yosuke Nishigaya, Shohei Takase, Tatsunobu Sumiya et al. · Journal of Medicinal Chemistry · 2023 · 25 citations · Full text

Novel pyrazolo[1,5-a]pyridines as orally active EP1 receptor antagonists: Synthesis, structure-activity relationship studies, and biological evaluation

Kentaro Umei, Yosuke Nishigaya, Atsushi Kondo et al. · Bioorganic & Medicinal Chemistry · 2017 · 21 citations · Full text

Discovery of novel pyrazolo[1,5-a]pyridine-based EP1 receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationships

Yosuke Nishigaya, Kentaro Umei, Yoshifumi Saito et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 18 citations · Full text

Drug Target, Scaffold Hopping, Biochemistry +10