Fumiyuki Shirai

<scp>RK</scp>‐287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model

Anna Mizutani, Yoko Yashiroda, Yukiko Muramatsu et al. · Cancer Science · 2018 · 78 citations · Full text

Medicine, Oncology, Pharmacology +17

Molecular basis for the binding of SH3 ligands with non-peptide elements identified by combinatorial synthesis

Sibo Feng, Tarun M. Kapoor, Fumiyuki Shirai et al. · Chemistry & Biology · 1996 · 60 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

Fumiyuki Shirai, Takeshi Tsumura, Yoko Yashiroda et al. · Journal of Medicinal Chemistry · 2019 · 57 citations · Full text

Medicine, Medicinal Chemistry, Oncology +14

A new approach to the chiral synthesis of the 1-.beta.-methylcarbapenem key precursor using an achiral ketone Sn(II) enolate

Fumiyuki Shirai, Takeshi Nakai · The Journal of Organic Chemistry · 1987 · 53 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Exploring the Leucine-Proline Binding Pocket of the Src SH3 Domain Using Structure-Based, Split-Pool Synthesis and Affinity-Based Selection

James P. Morken, Tarun M. Kapoor, Sibo Feng et al. · Journal of the American Chemical Society · 1998 · 48 citations

Life Sciences, Biochemistry, Molecular Biology +17