Ismail M. Hafez

Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.7K citations

Lipid Preparation, Nanomedicine, Engineering +3

Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**

Muthusamy Jayaraman, Steven M. Ansell, Barbara L. Mui et al. · Angewandte Chemie International Edition · 2012 · 1.2K citations · Full text

Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core

Alex K. K. Leung, Ismail M. Hafez, Svetlana Baoukina et al. · The Journal of Physical Chemistry C · 2012 · 344 citations

Nanoparticles, Proteinlipid Interaction, Engineering +17

Microfluidic Mixing: A General Method for Encapsulating Macromolecules in Lipid Nanoparticle Systems

Alex K. K. Leung, Yuen Yi C. Tam, Sam Chen et al. · The Journal of Physical Chemistry B · 2015 · 336 citations

Nanoparticles, Ethylene Glycol, Engineering +18

Bottom-Up Design and Synthesis of Limit Size Lipid Nanoparticle Systems with Aqueous and Triglyceride Cores Using Millisecond Microfluidic Mixing

Igor V. Zhigaltsev, Nathan M. Belliveau, Ismail M. Hafez et al. · Langmuir · 2012 · 332 citations

Nanoparticles, Lipid Preparation, Engineering +12