Dominique Westbrook

Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5- <i>d</i> ]azepines as Potent 5-Hydroxytryptamine 2C (5-HT _2C ) Receptor Agonists with Exquisite Functional Selectivity over 5-HT _2A and 5-HT _2B Receptors

Richard Storer, Paul E. Brennan, Alan D. Brown et al. · Journal of Medicinal Chemistry · 2014 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

N-[(3S)-Pyrrolidin-3-yl]benzamides as novel dual serotonin and noradrenaline reuptake inhibitors: Impact of small structural modifications on P-gp recognition and CNS penetration

Florian Wakenhut, Gill Allan, Paul V. Fish et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 13 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Using UV photoaged photography to better understand Western Australian teenagers’ attitudes towards adopting sun-protective behaviors

Myra F. Taylor, Dominique Westbrook, Paul Chang · International Journal of Adolescent Medicine and Health · 2015 · 13 citations · Full text

Public Health, Health Behavior, Psychology +16

Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: Design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence

Mark D. Andrews, Paul V. Fish, Julian Blagg et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 12 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11