Florian Wakenhut

Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space

Alexander Alex, David S. Millan, Manuel Pérez et al. · MedChemComm · 2011 · 323 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action

Paul Targett‐Adams, Emily J. S. Graham, Jenny Middleton et al. · Journal of Virology · 2011 · 120 citations

Medicine, Molecular Biology, Pharmacology +17

Palladium-Catalyzed Synthesis of Benzimidazoles and Quinazolinones from Common Precursors

Jessie E. R. Sadig, Radleigh A. A. Foster, Florian Wakenhut et al. · The Journal of Organic Chemistry · 2012 · 97 citations

Natural Sciences, Chemistry, Catalysis +10

Design and Synthesis of a Pan-Janus Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin

Peter Jones, Richard Storer, Yogesh Sabnis et al. · Journal of Medicinal Chemistry · 2016 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile—Part 1

Thien Duc Tran, Florian Wakenhut, Chris Pickford et al. · ChemMedChem · 2014 · 31 citations

Medicine, Infectious Diseases, Pharmacology +17