David S. Millan

Intramolecular hydrogen bonding to improve membrane permeability and absorption in beyond rule of five chemical space

Alexander Alex, David S. Millan, Manuel Pérez et al. · MedChemComm · 2011 · 323 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Total synthesis of (+)-phorboxazole A, a potent cytostatic agent from the sponge Phorbas sp.

Gerald Pattenden, Miguel A. González, Paul B. Little et al. · Organic & Biomolecular Chemistry · 2003 · 100 citations

Natural Sciences, Chemistry, Medicinal Chemistry +16

Design and Synthesis of Inhaled p38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease

David S. Millan, Mark E. Bunnage, Jane L. Burrows et al. · Journal of Medicinal Chemistry · 2011 · 95 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Clinical Candidate 4-[2-(5-Amino-1<i>H</i>-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-<i>N</i>-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of Na_V1.7

Nigel A. Swain, D. V. Batchelor, Serge Beaudoin et al. · Journal of Medicinal Chemistry · 2017 · 83 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

Bromonium Ion Induced Transannular Oxonium Ion Formation−Fragmentation in Model Obtusallene Systems and Structural Reassignment of Obtusallenes V−VII

D. Christopher Braddock, David S. Millan, Yolanda Pérez-Fuertes et al. · The Journal of Organic Chemistry · 2009 · 67 citations

Natural Sciences, Chemistry, Bioorganic Chemistry +15