Hirokazu Ikeda

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.

T Furitsu, Tohru Tsujimura, T. Tono et al. · Journal of Clinical Investigation · 1993 · 820 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines

H Kitayama, Yuzuru Kanakura, T Furitsu et al. · Blood · 1995 · 287 citations

Medicine, Molecular Biology, Oncology +16

Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells

Hanako Daino, Itaru Matsumura, Koji Takada et al. · Blood · 2000 · 114 citations

Life Sciences, Cell Biology, Hematology +16

Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor–induced chemotaxis: contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration

Shuji Ueda, Masao Mizuki, Hirokazu Ikeda et al. · Blood · 2002 · 112 citations

Life Sciences, Cell Biology, Molecular Biology +17

Induction of programmed cell death in human hematopoietic cell lines by fibronectin via its interaction with very late antigen 5.

Hiroyuki Sugahara, Yuzuru Kanakura, T Furitsu et al. · The Journal of Experimental Medicine · 1994 · 91 citations · Full text

Life Sciences, Cell Biology, Hematology +14