Marc Lake

Species differences and molecular determinant of TRPA1 cold sensitivity

Jun Chen, Dawon Kang, Jing Xu et al. · Nature Communications · 2013 · 229 citations · Full text

Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-R_S

Chaohong Sun, Danying Song, Rachel Davis‐Taber et al. · Proceedings of the National Academy of Sciences · 2007 · 136 citations · Full text

Activation of TRPA1 Channels by the Fatty Acid Amide Hydrolase Inhibitor 3′-Carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597)

Wende Niforatos, Xufeng Zhang, Marc Lake et al. · Molecular Pharmacology · 2007 · 69 citations

An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy

Sarah Chan, Nicole A. Belmar, Sun K. Ho et al. · Nature Cancer · 2022 · 66 citations · Full text

Discovery, Structure−Activity Relationship, and Pharmacological Evaluation of (5-Substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as Potent Dipeptidyl Peptidase IV Inhibitors

Zhonghua Pei, Xiaofeng Li, Kenton L. Longenecker et al. · Journal of Medicinal Chemistry · 2006 · 61 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +14