Jun Chen

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

Jun Chen, Shailen K. Joshi, Stanley DiDomenico et al. · Pain · 2011 · 269 citations · Full text

Species differences and molecular determinant of TRPA1 cold sensitivity

Jun Chen, Dawon Kang, Jing Xu et al. · Nature Communications · 2013 · 229 citations · Full text

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin

Hui Xu, Tianbo Li, Alexis Rohou et al. · Cell · 2019 · 181 citations · Full text

Nav1.7 Inhibition, Molecular Physiology, Toxinology +8

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

Alessia Balestrini, Victory Joseph, Michelle Dourado et al. · The Journal of Experimental Medicine · 2021 · 127 citations · Full text

Inflammation, Asthma, Trpa1 Inhibitor +15

Pore Dilation Occurs in TRPA1 but Not in TRPM8 Channels

Jun Chen, Donghee Kim, Bruce R. Bianchi et al. · Molecular Pain · 2009 · 116 citations · Full text

Trpa1 Activation, Signal Transduction, Molecular Physiology +15