Shailen K. Joshi

A-803467, a potent and selective Na _v 1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

Michael F. Jarvis, Prisca Honoré, Char‐Chang Shieh et al. · Proceedings of the National Academy of Sciences · 2007 · 523 citations · Full text

Medicine, Neurobiology, Pharmacology +17

Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation

Jun Chen, Shailen K. Joshi, Stanley DiDomenico et al. · Pain · 2011 · 271 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia

Prisca Honoré, Prasant Chandran, Gricelda Hernandez et al. · Pain · 2009 · 146 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Estimating Efficacy and Drug ED50's Using von Frey Thresholds: Impact of Weber's Law and Log Transformation

Charles D. Mills, David LeBlond, Shailen K. Joshi et al. · Journal of Pain · 2012 · 136 citations

Public Health, Pharmacology, Dose-response Modeling +8

Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Na_v1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pain

Michael E. Kort, Irene Drizin, Robert J. Gregg et al. · Journal of Medicinal Chemistry · 2008 · 85 citations · Full text

Medicine, Neuroscience, Pharmacology +17