A-803467, a potent and selective Na _v 1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat

Michael F. Jarvis, Prisca Honoré, Char‐Chang Shieh, +34

Proceedings of the National Academy of Sciences

Involvement of the TTX-resistant sodium channel Nav 1.8 in inflammatory and neuropathic, but not post-operative, pain states

S. K. Joshi, Joseph P. Mikusa, Gricelda Hernandez, +12

Pain

Inactivation of Kv2.1 Potassium Channels

Kathryn G. Klemic, Char‐Chang Shieh, Glenn E. Kirsch, +1

Biophysical Journal

ChannelopathiesMolecular PhysiologyHyperpolarization (Biology)NeurophysiologyKv2.1 Potassium Channels +9

Potassium channels Kv1.1, Kv1.2 and Kv1.6 influence excitability of rat visceral sensory neurons

Patricia A. Glazebrook, Angelina N. Ramirez, John H. Schild, +4

The Journal of Physiology

Synaptic TransmissionPotassium Channels Kv1.1NeurotransmissionKv1 FamilyCellular Neurobiology +14

K+ pore structure revealed by reporter cysteines at inner and outer surfaces

Juan M. Pascual, Char‐Chang Shieh, Glenn E. Kirsch, +1

Neuron

Pore StructureBiochemistryNatural SciencesBiophysical AspectOuter Surfaces +8

Effects of intermediate-conductance Ca2+-activated K+ channel modulators on human prostate cancer cell proliferation

Michael J. Coghlan, Murali Gopalakrishnan, Char‐Chang Shieh

European Journal of Pharmacology

UrologySignal TransductionHyperpolarization (Biology)Cell SignalingPhysiology +5

Decreased Sodium and Increased Transient Outward Potassium Currents in Iron-Loaded Cardiac Myocytes

Yuri A. Kuryshev, Gary M. Brittenham, Hisashi Fujioka, +4

Circulation

Validation of FLIPR Membrane Potential Dye for High Throughput Screening of Potassium Channel Modulators

Kristi L. Whiteaker, Sujatha M. Gopalakrishnan, Duncan R. Groebe, +6

SLAS DISCOVERY

BiochemistryHigh Throughput ScreeningMembrane TransportIon ChannelsMembrane Characterization +5

Discovery and Biological Evaluation of 5-Aryl-2-furfuramides, Potent and Selective Blockers of the Na_v1.8 Sodium Channel with Efficacy in Models of Neuropathic and Inflammatory Pain

Michael E. Kort, Irene Drizin, Robert J. Gregg, +27

Journal of Medicinal Chemistry

Pain DisordersPain MedicineNeuropathic PainMolecular PainPharmacotherapy +18

Functional expression of P2X7 receptors in non-neuronal cells of rat dorsal root ganglia

Xu‐Feng Zhang, Ping Han, Connie R. Faltynek, +2

Brain Research

Molecular PhysiologyFunctional ExpressionNon-neuronal CellsMedicinePhysiology +12