John S. Elder

Nanomolar Inhibitors of <i>Staphylococcus </i><i>a</i><i>ureus</i> Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Richard L. Jarvest, John M. Berge, Valerie Berry et al. · Journal of Medicinal Chemistry · 2002 · 102 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Definition of the heterocyclic pharmacophore of bacterial methionyl tRNA synthetase inhibitors: potent antibacterially active non-quinolone analogues

Richard L. Jarvest, Sula A Armstrong, John M. Berge et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and antibacterial properties of β-diketone acrylate bioisosteres of pseudomonic acid A

Isobel Bennett, N. J. P. BROOM, Robert Cassels et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 38 citations

Pharmacy, Chemistry, Medicinal Chemistry +11

Acetonitrile: an excellent solvent for the 1,1-dichloromethylenation of certain ketones

George Burton, John S. Elder, Stephen C. M. Fell et al. · Tetrahedron Letters · 1988 · 37 citations

Natural Sciences, Chemistry, Organic Chemistry +2

Optimisation of aryl substitution leading to potent methionyl tRNA synthetase inhibitors with excellent gram-Positive antibacterial activity

Richard L. Jarvest, John M. Berge, Murray J. B. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14