The Chemistry of Pseudomonic Acid. 18. Heterocyclic Replacement of the α,β-Unsaturated Ester:  Synthesis, Molecular Modeling, and Antibacterial Activity

Pamela Brown, DESMOND J. BEST, N. J. P. BROOM, +5

Journal of Medicinal Chemistry

Occurrence of the regulatory nucleotides ppGpp and pppGpp following induction of the stringent response in staphylococci

Robert Cassels, B Oliva, Donald P. Knowles

Journal of Bacteriology

EngineeringGeneticsBacteriologyMolecular BiologyEscherichia Coli +15

Study of the Tryptophan Residues of Lysozyme Using ¹H Nuclear Magnetic Resonance

Robert Cassels, Christopher M. Dobson, Flemming M. Poulsen, +1

European Journal of Biochemistry

Isolation of dihydroclavaminic acid, an intermediate in the biosynthesis of clavulanic acid

Jack E. Baldwin, Robert M. Adlington, Justin S. Bryans, +9

Tetrahedron

BiosynthesisBioorganic ChemistryClavulanic AcidBiochemistryNatural Sciences +6

SB-203207 and SB-203208, Two Novel Isoleucyl tRNA Synthetase Inhibitors from a Streptomyces sp. I. Fermentation, Isolation and Properties.

Anna L. Stefanska, Robert Cassels, Sarah Ready, +1

The Journal of Antibiotics

Evidence that the immediate biosynthetic precursor of clavulanic acid is its N-aldehyde analogue

Neville Nicholson, Keith H. Baggaley, Robert Cassels, +5

Journal of the Chemical Society Chemical Communications

EngineeringSecondary MetaboliteS. R. WoronieckiChemistrySpectra-structure Correlation +17

Joshua: uniform access to heterogeneous knowledge structures or why joshing is better than conniving or planning

Steve Rowley, Howard Shrobe, Robert Cassels, +1

National Conference on Artificial Intelligence

EngineeringSoftware EngineeringSoftware AnalysisFormal VerificationJoshua Programmer +23

Synthesis and antibacterial properties of β-diketone acrylate bioisosteres of pseudomonic acid A

Isobel Bennett, N. J. P. BROOM, Robert Cassels, +3

Bioorganic & Medicinal Chemistry Letters

Antibacterial PropertiesOrganic ChemistryAntimicrobial CompoundChemistryPseudomonic Acid A +2

Structure and binding properties of hen lysozyme modified at tryptophan 62

C. C. F. Blake, Robert Cassels, Christopher M. Dobson, +3

Journal of Molecular Biology

Protein ChemistryBiochemistryProtein FoldingNatural SciencesHen Lysozyme +6

Physical and Chemical Properties of Lysozyme

C. C. F. Blake, David Grace, L.N. Johnson, +6

Novartis Foundation symposium