Mengkun Zhang

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

Dragan Jovanović, John A. Di Battista, Johanne Martel‐Pelletier et al. · The Journal of Immunology · 1998 · 851 citations · Full text

Immunology, Immune Regulation, Immunologic Mechanism +21

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

Mark Manfredi, Jeffrey Ecsedy, Kristan Meetze et al. · Proceedings of the National Academy of Sciences · 2007 · 413 citations · Full text

Tumor Biology, Active Small-molecule Inhibitor, Antitumor Activity +15

Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel <i>In Vivo</i> Pharmacodynamic Assays

Mark Manfredi, Jeffrey Ecsedy, Arijit Chakravarty et al. · Clinical Cancer Research · 2011 · 298 citations

MLN8054, an Inhibitor of Aurora A Kinase, Induces Senescence in Human Tumor Cells Both <i>In vitro</i> and <i>In vivo</i>

Jessica J. Huck, Mengkun Zhang, Alice McDonald et al. · Molecular Cancer Research · 2010 · 117 citations

Cancer Research, Aurora A Kinase, Cell Regulation +14

MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors

Todd B. Sells, Ryan Chau, Jeffrey Ecsedy et al. · ACS Medicinal Chemistry Letters · 2015 · 108 citations · Full text

Aurora A, Immunology, Molecular Biology +19