Concepedia

Ryan Chau

RC

Statistics

Publications

10

Citations

743

H-Index

10

Active since

2005

Affiliations

Millennium Engineering and Integration (United States)(Current)

Takeda (United States)

Merck & Co., Inc., Rahway, NJ, USA (United States)

Ryan Chau is an author at Millennium Engineering and Integration (United States) specializing in medicine, drug discovery, and pharmacology.

Top concepts

MedicinePharmacologyDrug DiscoveryTumor BiologyCancer ResearchMedicinal ChemistryPharmacotherapyDrug DevelopmentTumor MicroenvironmentOncology

Publications per year

2005–2022

10

Publications

10

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

Xingyue He, Jessica Riceberg, Teresa A. Soucy et al. · Nature Chemical Biology · 2017 · 223 citations

Selective Sae Inhibitor, Oncogenic Agent, Medicine +10

Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer

Steven Langston, Stephen Grossman, Dylan B. England et al. · Journal of Medicinal Chemistry · 2021 · 194 citations · Full text

MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors

Todd B. Sells, Ryan Chau, Jeffrey Ecsedy et al. · ACS Medicinal Chemistry Letters · 2015 · 108 citations · Full text

Aurora A, Immunology, Molecular Biology +19

Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)

Matthew O. Duffey, Tricia J. Vos, Ruth Adams et al. · Journal of Medicinal Chemistry · 2011 · 54 citations · Full text

Pharmacotherapy, Pharmaceutical Chemistry, Tumor Biology +18

Novel Indole Chemistry in the Synthesis of Heterocycles

Gordon W. Gribble, Mark G. Saulnier, Erin T. Pelkey et al. · Current Organic Chemistry · 2005 · 45 citations

Successful Electrophilic Trapping, Engineering, Heterocyclic +8

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