Judith E. Grolleman

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer

Jarno Drost, Ruben van Boxtel, Francis Blokzijl et al. · Science · 2017 · 454 citations · Full text

Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype

Judith E. Grolleman, Richarda M. de Voer, Fadwa A. Elsayed et al. · Cancer Cell · 2019 · 166 citations · Full text

Tumor Biology, Multi-tumor Phenotype, Somatic Variant +11

Germline MBD4 deficiency causes a multi-tumor predisposition syndrome

Claire Palles, Hannah D. West, Edward Chew et al. · The American Journal of Human Genetics · 2022 · 72 citations · Full text

Monoallelic NTHL1 Loss-of-Function Variants and Risk of Polyposis and Colorectal Cancer

Fadwa A. Elsayed, Judith E. Grolleman, Abiramy Ragunathan · Gastroenterology · 2020 · 30 citations · Full text

Contribution of New Adenomatous Polyposis Predisposition Genes in an Unexplained Attenuated Spanish Cohort by Multigene Panel Testing

Víctor Lorca, Daniel Rueda, Lorena Martín-Morales et al. · Scientific Reports · 2019 · 14 citations · Full text