Edward Chew

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Rachel Thijssen, Sarah T. Diepstraten, Donia M. Moujalled et al. · Blood · 2021 · 135 citations · Full text

Medicine, Cancer Biology, Oncology +12

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Mathijs A. Sanders, Edward Chew, Christoffer Flensburg et al. · Blood · 2018 · 115 citations · Full text

Life Sciences, Genetics, Hematology +17

Standardized practices for RNA diagnostics using clinically accessible specimens reclassifies 75% of putative splicing variants

Adam Bournazos, Lisa G. Riley, Shobhana Bommireddipalli et al. · Genetics in Medicine · 2021 · 104 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

The BH3 mimetic compound, ABT-737, synergizes with a range of cytotoxic chemotherapy agents in chronic lymphocytic leukemia

Kylie D. Mason, Seong Lin Khaw, Kathleen C. Rayeroux et al. · Leukemia · 2009 · 98 citations

Medicine, Oncology, Pharmacology +8

Germline MBD4 deficiency causes a multi-tumor predisposition syndrome

Claire Palles, Hannah D. West, Edward Chew et al. · The American Journal of Human Genetics · 2022 · 77 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17