Warren D. Hirst

Activation of estrogen receptor-β regulates hippocampal synaptic plasticity and improves memory

Feng Liu, Mark L. Day, Luis C Muñiz et al. · Nature Neuroscience · 2008 · 506 citations

Life Sciences, Neurobiology, Neuroscience +10

GSK189254, a Novel H3 Receptor Antagonist That Binds to Histamine H3 Receptors in Alzheimer’s Disease Brain and Improves Cognitive Performance in Preclinical Models

Andrew D. Medhurst, A.R. Atkins, I.J.M. Beresford et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 301 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Epileptogenesis and Enhanced Prepulse Inhibition in GABAB1-Deficient Mice

Haydn M. Prosser, Catherine H. Gill, Warren D. Hirst et al. · Molecular and Cellular Neuroscience · 2001 · 282 citations

Medicine, Neurobiology, Neuroscience +14

Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression

Anastasia G. Henry, Soheil Aghamohammadzadeh, Harry Samaroo et al. · Human Molecular Genetics · 2015 · 249 citations · Full text

Life Sciences, Neurology, Neuroscience +15

The LXR agonist TO901317 selectively lowers hippocampal Aβ42 and improves memory in the Tg2576 mouse model of Alzheimer's disease

David Riddell, Hua Zhou, Thomas A. Comery et al. · Molecular and Cellular Neuroscience · 2007 · 248 citations

Life Sciences, Neuroscience, Pharmacology +16