Concepedia

The LXR agonist TO901317 selectively lowers hippocampal Aβ42 and improves memory in the Tg2576 mouse model of Alzheimer's disease

David Riddell, Hua Zhou, Thomas A. Comery, Evguenia Kouranova, Cody Lo, Helen K. Warwick, Robert H. Ring, Yolanda Kirksey, Suzan Aschmies, Jane Xu,

Molecular and Cellular Neuroscience · 2007 · 248 citations · 28 references

DOI

Concepts

References

28

RETRACTED ARTICLE: A specific amyloid-β protein assembly in the brain impairs memory

Sylvain Lesné, Ming Teng Koh, Linda Kotilinek et al. · Nature · 2006 · 2.8K citations

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Role of LXRs in control of lipogenesis

Joshua R. Schultz, Hua Tu, Alvin Luk et al. · Genes & Development · 2000 · 1.7K citations · Full text

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Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

Mikael Simons, Patrick Keller, Bart De Strooper et al. · Proceedings of the National Academy of Sciences · 1998 · 1.2K citations

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Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

Robert Ehehalt, Patrick Keller, Christian Haass et al. · The Journal of Cell Biology · 2003 · 1.1K citations · Full text

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Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 <i>in vitro</i> and <i>in vivo</i>

Mikael Simons, Christine Bergmann, Mark Stroick et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

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