Brigitte Baldeyrou

Topoisomerase I-mediated DNA cleavage as a guide to the development of antitumor agents derived from the marine alkaloid lamellarin D: triester derivatives incorporating amino acid residues

Christelle Tardy, Michaël Facompré, William Laine et al. · Bioorganic & Medicinal Chemistry · 2004 · 104 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues : A novel DYRK1A inhibitor class

Cléopatra Neagoie, Emeline Vedrenne, Frédéric Buron et al. · European Journal of Medicinal Chemistry · 2012 · 99 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Alkaloids from<i>Cassytha filiformis</i>and Related Aporphines: Antitrypanosomal Activity, Cytotoxicity, and Interaction with DNA and Topoisomerases

Sara Hoet, Caroline Stévigny, Sébastien Block et al. · Planta Medica · 2004 · 94 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells

Laurent Dassonneville, Nicole Wattez, Brigitte Baldeyrou et al. · Biochemical Pharmacology · 2000 · 79 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Synthesis, Cytotoxicity, DNA Interaction, and Topoisomerase II Inhibition Properties of Novel Indeno[2,1-<i>c</i>]quinolin-7-one and Indeno[1,2-<i>c</i>]isoquinolin-5,11-dione Derivatives

Adina Ryckebusch, Deborah Garcin, Amélie Lansiaux et al. · Journal of Medicinal Chemistry · 2008 · 66 citations

Medicine, Medicinal Chemistry, Pharmacology +12